He has played many roles inside film and television, perhaps virtually all notably voicing a parrot Iago in Disney's Aladdin (1992) and co-starring in the Problem Child movies (1990 and 1991). He is too a voice of the duck in the AFLAC commercials and of Digit in the math-mystery cartoon Cyberchase on PBS Kids GO!. Gottfried makes regular appearances on The Tonight Show with Jay Leno and appeared in the 2005 documentary The Aristocrats, which included footage of Gottfried's legendary re-telling around 2001 of the dirty joke at the Friars Club roast of Hugh Hefner just three weeks when a September 11 terrorist attacks: He experienced at the start touched on the sensitive topic, joking that he had designed to catch the plane to California, but couldn't acquire the straight flight because "they said they have to stop at the Empire State Building first." As audience members responded sustaining pant & cries of "too soon!", he launched into the version of the Aristocrats joke that brought down a house & became the highlight of the evening. A occasion is okay, widely regarded as an crucial & decisive moment around have-higher comedy.

From either 1980 to 1981, he was a cast member of the NBC late night series Saturday Night Live. Through the late 1980s and much of the 1990s, he was co-host (foremost by having Caroline Schlitt, then by having Rhonda Shear) of the USA Network late-night film showcase, "USA's Up All Night".

Inside July 2005, The New Yorker revealed that high school dropout Gottfried, notorious for his sparing loner life style, might go into the recently $3 million Manhattan apartment with the longtime girlfriend.

Gottfried is releasing his latest have-higher DVD entitled "Gilbert Gottfried's Dirty Jokes" within December 2005.